Ursolic acid is a pentacyclic triterpene substance, which was first discovered in the epidermal wax of apples in 1920. Ursolic acid is also present in the peels of many plants and herbs such as rosemary and thyme.

Ursolic acid is present in many plants, such as Mirabilis and many fruits and herbs used in daily life (such as apple, basil, bilberry, cranberry, elderflower, mint, rosemary, lavender, oregano, thyme) , Hawthorn and plum). Apple peel contains a lot of ursolic acid and related compounds.

Ursolic acid is an organic compound with a molecular formula of C30H48O3. It is a natural triterpene carboxylic acid compound with preventive and anti-cancer activities. It can be used as an emulsifier for medicines and foods.

Ursolic acid is a kind of triterpenoid compound that exists in natural plants. Ursolic acid has many benefits, such as sedative, anti-inflammatory, antibacterial, anti-diabetic, anti-ulcer, lowering blood sugar and other biological effects. Acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics.

The clinical manifestations of ursolic acid can significantly and rapidly reduce alanine aminotransferase, serum aminotransferase, reduce jaundice, increase appetite, anti-fibrosis and restore liver function. It has the characteristics of quick effect, short course of treatment and stable effect.

Indian scholar Saraswat et al. found that ursolic acid (5-20 mg•kg) has a protective effect on rat liver toxicity caused by CC1. Using ursolic acid as pretreatment can significantly increase the survival rate of rat liver cells, and it has been observed in experiments that ursolic acid has an anti-cholestotic effect, and the bile flow and its contents are increased. 

According to the mechanism of CC1, it is speculated that the therapeutic mechanism of ursolic acid on damaged liver cells may be similar to its isomer oleanolic acid, which is to protect and stabilize the biomembrane system of liver cell membranes and organelles, making changes transparent and active. 

The transport function returns to normal, and the movement and distribution of ions and water inside and outside the cells are also restored, and the regeneration ability is successively restored, which promotes the repair of necrotic liver cells in the central area of liver lobules.

Ursolic acid is a strong antioxidant. Experiments have shown that ursolic acid can inhibit the activities of 5-lipoxygenase and cyclooxygenase during the metabolism of arachidonic acid, and prevent the production of prostaglandins and leukotrienes. 

This may be because ursolic acid inhibits inflammation and inhibits lipid metabolism. The cause of oxide. Subbaramaiah and other studies have shown that ursolic acid can inhibit the transcription of cyclooxygenase in human breast epithelial cells, thereby inhibiting prostaglandin production. Ursolic acid has obvious stabilizing and cooling effects on the central nervous system.

Nutra-herb Ingredients Inc. sells ursolic acid for food and dietary supplements. If you need to buy ursolic acid, please contact us.

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